Stroke: June 1, 2013 The only treatment shown to improve outcome in acute ischemic stroke is tissue-type plasminogen activator administered within 3 hours (and perhaps longer) after stroke onset.1–3 Definitive data to support a role for acute endovascular stroke therapy, however, are lacking. Despite this lack of data, endovascular therapy is being used much more widely […]
Stroke: June 1, 2013 The benefit of intravenous recombinant tissue-type plasminogen activator (rt-PA) for the treatment of acute ischemic stroke is well established.1,2 Unfortunately, the rates of rt-PA use among US patients with ischemic stroke remain quite low. Previously, our group published the rate of rt-PA use among ischemic stroke patients within the large Premier database, […]
Annals of Neurology: May 30, 2013 ABSTRACT Approximately 700,000 people in the United States have an ischemic stroke annually. Substantial research has tested therapies for the very early treatment of ischemic stroke but, to date, only intravenous thrombolysis and intra-arterial measures to restore perfusion have shown success. Despite a 15-year effort to increase the use […]
Annals of Neurology: May 30, 2013 Abstract OBJECTIVE: This meta-analysis aims to quantitatively synthesize all studies that examine the association between adherence to a Mediterranean diet and risk of stroke, depression, cognitive impairment and Parkinson’s disease. METHODS: Potentially eligible publications were those providing effect estimates of relative risk (RR) for the association between Mediterranean diet […]
Neurology May 28, 2013 Objective: To assess evidence regarding periprocedural management of antithrombotic drugs in patients with ischemic cerebrovascular disease. The complete guideline on which this summary is based is available as an online data supplement to this article. Methods: Systematic literature review with practice recommendations. Results and recommendations: Clinicians managing antithrombotic medications periprocedurally must weigh bleeding risks from […]
