Stroke Reports
Tuesday, September 17th, 2013
Wiley: 9/12/13 Limited studies exist on the outcome of thrombolytic therapy of acute ischemic stroke patients outside of clinical trials. Aim To assess the possible risk factors associated with in-hospital death and symptomatic intracerebral hemorrhage among patients who received intravenous tissue plasminogen activator. Methods A total of 7193 patients with a clinical diagnosis of acute ischemic […]
Stroke Reports
Tuesday, September 17th, 2013
STROKEAHA: September 10, 2013 Background and Purpose—Many patients are transferred to comprehensive stroke centers for advanced acute ischemic stroke care, especially after intravenous tissue plasminogen activator. We sought to determine differences in the baseline characteristics and outcomes between patients with acute ischemic stroke presenting directly to our academic stroke center’s front door versus transfers-in from another […]
Stroke Reports
Tuesday, September 17th, 2013
Wiley: 9/5/13 Reliable estimates of intracluster correlation coefficients (ICCs) for specific outcome measures are crucial for sample size calculations of future cluster randomized trials. ICCs indicate the proportion of data variability that is explained by defined levels of clustering. Aims In this manuscript, we present potentially valuable and reliable estimates of ICCs for specific baseline and […]
Stroke Reports
Tuesday, September 17th, 2013
CIRCULATIONAHA: August 9, 2013 Background—Limited long-term follow-up data exist on the impact of appropriate secondary prevention therapies on cognitive function in patients after first-ever stroke. The aim of this study is to determine the effect of secondary prevention of vascular events on cognitive function after stroke. Methods and Results—Data were collected between 1995 and 2011 (n=4413) […]
Stroke Reports
Thursday, September 5th, 2013
STROKEAHA: September 3, 2013 Background and Purpose—Although both ends of the hemoglobin range may negatively influence clinical outcomes in acute ischemic stroke, most studies have examined the linear relationship or focused on the lower end of the range. Furthermore, it is unclear whether hemoglobin concentrations at different time points during hospitalization correlate with clinical outcomes in […]
Stroke Reports
Thursday, September 5th, 2013
STROKEAHA: September 3, 2013 Background and Purpose—Intracerebral hemorrhage is a serious potential complication of stroke thrombolysis. We investigated the optimal computed tomography perfusion (CTP) parameter to predict cerebral parenchymal hematoma (PH) in acute ischemic stroke. Methods—Patients with hyperacute ischemic stroke had whole-brain CTP and follow-up computed tomography/MRI to identify hemorrhagic transformation. The association of the 3 […]
Stroke Reports
Thursday, September 5th, 2013
STROKEAHA: September 3, 2013 Background and Purpose—To determine the effect of intravenous tissue plasminogen activator (IV-tPA) on outcomes in patients with severe major anterior circulation ischemic stroke. Methods—Prospectively, 649 patients with acute stroke had admission National Institutes of Health stroke scale (NIHSS) scores, noncontrast computed tomography (CT), CT angiography (CTA), and 6-month outcome assessed using modified […]
Stroke Reports
Thursday, September 5th, 2013
STROKEAHA: September 3, 2013 Background and Purpose—Little is known about the distribution of National Institutes of Health Stroke Scale (NIHSS) scores from patients with ischemic stroke sampled from population-based studies. We describe the distribution of NIHSS in ischemic stroke cases from the Cincinnati/Northern Kentucky Stroke Study. Methods—Within a biracial population of 1.3 million, all strokes among […]
Stroke Reports
Thursday, September 5th, 2013
STROKEAHA: 7/29/13 Background and Purpose—To investigate the association of low estimated glomerular filtration rate (eGFR) <60 mL/min with recurrent stroke risk and to evaluate whether add-on renin–angiotensin system modulator therapy is associated with lower recurrent stroke risk in patients with low eGFR. Methods—We analyzed the database of a multicenter trial involving 18 666 patients with […]
