Stroke Reports
Friday, November 22nd, 2013
STROKEAHA: November 21, 2013 Background and Purpose—Ischemic stroke (IS) and coronary artery disease (CAD) share several risk factors and each has a substantial heritability. We conducted a genome-wide analysis to evaluate the extent of shared genetic determination of the two diseases. Methods—Genome-wide association data were obtained from the METASTROKE, Coronary Artery Disease Genome-wide Replication and Meta-analysis […]
Stroke Reports
Friday, November 22nd, 2013
AHA: 11/21/13 Background and Purpose—Temporal variations of thrombolysis delivery and their influence on outcome have been reported with controversial results. In this large cohort study, we evaluated whether thrombolytic treatment has a within-day and weekly variability corresponding to circadian and weekly patterns of ischemic stroke onset, and whether these have impact on clinical outcome. Methods—We […]
Stroke Reports
Friday, November 22nd, 2013
Wiley: 11/21/13 The currently proven time window for thrombolysis in ischemic stroke is 4·5 h. Beyond this, the risks and benefits of thrombolysis are uncertain. Aims To determine whether thrombolysis and reperfusion were beneficial after 4·5 h, we examined clinical and radiological outcomes in patients treated with tissue plasminogen activator or placebo within 4·5–6 h, using data from the […]
Stroke Reports
Friday, November 22nd, 2013
STROKEAHA: November 19, 2013 Background and Purpose—Analysis of quality of care for in-hospital stroke has not been previously performed at the national level. This study compares patient characteristics, process measures of quality, and outcomes for in-hospital strokes with those for community-onset strokes in a national cohort. Methods—We performed a retrospective cohort study of the Get With […]
Stroke Reports
Friday, November 22nd, 2013
PLOS: 11/18/13 Various studies demonstrate better patient outcome and higher thrombolysis rates achieved by centralized stroke care compared to decentralized care, i.e. community hospitals. It remains largely unclear how to improve thrombolysis rate in decentralized care. The aim of this simulation study was to assess the impact of previously identified success factors in a central […]
Stroke Reports
Monday, November 18th, 2013
JAMA: 11/17/13 Importance Although the benefit of reducing blood pressure for primary and secondary prevention of stroke has been established, the effect of antihypertensive treatment in patients with acute ischemic stroke is uncertain. Objective To evaluate whether immediate blood pressure reduction in patients with acute ischemic stroke would reduce death and major disability at 14 days or hospital […]
Stroke Reports
Monday, November 18th, 2013
STROKEAHA: November 14, 2013 Background and Purpose—Patients with acute ischemic stroke benefit from rapid evaluation and treatment, and timely brain imaging is a necessary component. We determined the effect of a targeted behavioral intervention on door-to-imaging time (DIT) among patients with ischemic stroke treated with tissue-type plasminogen activator. Second, we examined the variation in DIT accounted […]
Stroke Reports
Monday, November 18th, 2013
AMA: 11/12/13 Preamble and Transition to ACC/AHA Guidelines to Reduce Cardiovascular Risk The goals of the American College of Cardiology (ACC) and the American Heart Association (AHA) are to prevent cardiovascular (CV) diseases, improve the management of people who have these diseases through professional education and research, and develop guidelines, standards and policies that promote […]
Stroke Reports
Monday, November 18th, 2013
STROKEAHA: November 7, 2013 Background and Purpose—Remote ischemic preconditioning is neuroprotective in models of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to treatment with intravenous alteplase in patients with acute ischemic stroke. Methods—Open-label blinded outcome proof-of-concept study of prehospital, paramedic-administered rPerC at a 1:1 ratio in consecutive patients with suspected […]
Stroke Reports
Monday, November 18th, 2013
STROKEAHA: October 31, 2013 Background and Purpose—Medical complications are common among patients with stroke. However, little is known about the potential interrelationship among them. In the present study, we aimed to investigate the association between common in-hospital medical complications after acute ischemic stroke (AIS) and spontaneous intracerebral hemorrhage (ICH). Methods—We analyzed patients enrolled in the China […]
