Stroke Incidence and Mortality Trends in US Communities, 1987 to 2011

JAMA: July 16, 2014 Importance  Prior studies have shown decreases in stroke mortality over time, but data on validated stroke incidence and long-term trends by race are limited. Objective  To study trends in stroke incidence and subsequent mortality among black and white adults in the Atherosclerosis Risk in Communities (ARIC) cohort from 1987 to 2011. Design, Setting, and Participants  Prospective cohort […]

Trends in 10-Year Survival of Patients With Stroke Hospitalized Between 1980 and 2000

STROKEAHA: uly 15, 2014 Abstract Background and Purpose—We report on trends in poststroke survival, both in the early period after stroke and over the long term. We examine these trends by stroke subtype. Methods—The Minnesota Stroke Survey is a study of all hospitalized patients with acute stroke aged 30 to 74 years in the Minneapolis–St Paul […]

Original research Comparison of endovascular treatment approaches for acute ischemic stroke: cost effectiveness, technical success, and clinical outcomes

J NeuroIntervent Surg:  23 June 2014 Introduction The use of mechanical thrombectomy for the treatment of acute ischemic stroke has significantly advanced over the last 5 years. Few data are available comparing the cost and clinical and angiographic outcomes associated with available techniques. The aim of this study is to compare the cost and efficacy of current endovascular […]

Standard-Dose Intravenous Tissue-Type Plasminogen Activator for Stroke Is Better Than Low Doses

STROKEAHA: July 10, 2014 Background and Purpose—It remains uncertain whether lower dose intravenous tissue-type plasminogen activator (tPA) for stroke is as effective and safe as the standard dose. Methods—We analyzed data from the Thrombolysis Implementation and Monitor of Acute Ischemic Stroke in China (TIMS-China). Patients who were treated within 4.5 hours after symptom onset were included. […]

iPad Technology for Home Rehabilitation after Stroke (iHOME): A proof-of-concept randomized trial

International Journal of Stroke: 7 JUL 2014 Background Tablets are a novel line of computers controlled by a multitouch screen. Fine motor movements are captured on the tablet computer through electrical fields and can be qualitatively and quantitatively assessed. Evidence is limited on tablet use for stroke rehabilitation. Read More

Inability to consent does not diminish the desirability of stroke thrombolysis

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Wiley: 9 JUL 2014 Objective Some have argued that physicians should not presume to make thrombolysis decisions for incapacitated patients with acute ischemic stroke because the risks and benefits of thrombolysis involve deeply personal values. We evaluated the influence of the inability to consent and of personal health-related values on older adults’ emergency treatment preferences for […]

Factors associated with unfavorable outcome in minor ischemic stroke

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Neurology: 7/8/14 Objectives: The purpose of this study was to elucidate the factors that correlate with unfavorable outcomes and to develop a simple validated model for assessing risk of unfavorable outcomes in patients with minor ischemic stroke. Methods: The derivation cohort included 1,313 patients hospitalized within 72 hours after onset with an initial NIH Stroke Scale score […]

Pittsburgh Outcomes After Stroke Thrombectomy Score Predicts Outcomes After Endovascular Therapy for Anterior Circulation Large Vessel Occlusions

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STROKEAHA: July 8, 2014 Background and Purpose—Prognostication tools that predict good outcome in patients with anterior circulation large vessel occlusions after endovascular therapy are lacking. We aim to develop a tool that incorporates clinical and imaging data to predict outcomes after endovascular therapy. Methods—In a derivation cohort of anterior circulation large vessel occlusion stroke patients treated […]

Recurrent thromboembolic events after ischemic stroke in patients with cancer

Neurology: May 21, 2014 Objective: To determine the cumulative rate and characteristics of recurrent thromboembolic events after acute ischemic stroke in patients with cancer. Methods: We retrospectively identified consecutive adult patients with active systemic cancer diagnosed with acute ischemic stroke at a tertiary-care cancer center from 2005 through 2009. Two neurologists independently reviewed all electronic records to ascertain […]

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial

The Lancet, Early Online Publication, 23 May 201. Background Thrombolysis is of net benefit in patients with acute ischaemic stroke, who are younger than 80 years of age and are treated within 4·5 h of onset. The third International Stroke Trial (IST-3) sought to determine whether a wider range of patients might benefit up to […]

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