Effect of Genetic Variants Associated With Plasma Homocysteine Levels on Stroke Risk

STROKEAHA: May 20, 2014

Background and Purpose—Elevated total plasma homocysteine (tHcy) levels are known to be associated with increased risk of ischemic stroke (IS). Given that both tHcy and IS are heritable traits, we investigated a potential genetic relationship between homocysteine levels and stroke risk by assessing 18 polymorphisms previously associated with tHcy levels for their association with IS and its subtypes. Read more

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