Intake of Dietary Phylloquinone and Menaquinones and Risk of Stroke

Stroke Reports Sunday, December 15th, 2013

J Am Heart Assoc: December 10, 2013

Background Dietary vitamin K intake is thought to decrease the risk of cardiovascular disease (CVD) by reducing vascular calcification, although vitamin K is also involved in coagulation. Studies investigating the association between phylloquinone intake and risk of stroke are scarce, and the relation with menaquinones has not been investigated to date.

Methods and Results We investigated the association between intake of phylloquinone and menaquinones and stroke in a prospective cohort of 35 476 healthy subjects. Information on occurrence of stroke was obtained by linkage to national registries, and stroke was further specified into ischemic and hemorrhagic stroke. Vitamin K intake was estimated using a validated food‐frequency questionnaire. Read More

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