Lack of progressive arteriopathy and stroke recurrence among children with cryptogenic stroke

Stroke Reports Friday, December 7th, 2012

Neurology.org: 11/28/12

Objective: We hypothesized that cryptogenic forms of arterial ischemic stroke (AIS) in children may present better outcomes than symptomatic ones.

Methods: We conducted a single-centered retrospective cohort study using chart reviews of all inpatients aged 0.25–16 years and admitted for AIS or TIA between 1994 and 2007. Sixty-three consecutive children with AIS were divided into 2 stroke categories: first, AIS with an established cause, considered as symptomatic (S), and second, AIS only associated with risk factors, and considered as cryptogenic (C). AIS were further subclassified according to the CASCADE stroke classification system. We measured long-term outcome with 2 endpoints: recurrence rate and neurologic impairment score (NIS). We used univariate analysis to compare the clinical and radiologic characteristics of both groups. Read more

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