Relationship Between Onset-to-Door Time and Door-to-Thrombolysis Time

Stroke Reports Friday, July 26th, 2013

STROKEAHA: July 25, 2013

 

A Pooled Analysis of 10 Dedicated Stroke Centers

Background and Purpose—Inverse relationship between onset-to-door time (ODT) and door-to-needle time (DNT) in stroke thrombolysis was reported from various registries. We analyzed this relationship and other determinants of DNT in dedicated stroke centers.

Methods—Prospectively collected data of consecutive ischemic stroke patients from 10 centers who received IV thrombolysis within 4.5 hours from symptom onset were merged (n=7106). DNT was analyzed as a function of demographic and prehospital variables using regression analyses, and change over time was considered. Read More

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