Stroke Reports
Saturday, January 26th, 2013
STROKEAHA: January 22, 2013 Background and Purpose—Therapeutic hypothermia improves clinical outcome after cardiac arrest and appears beneficial in other cerebrovascular diseases. We conducted this study to investigate the relationship between surface head/neck cooling and brain temperature. Methods—Prospective observational study enrolling consecutive patients with severe ischemic or hemorrhagic stroke undergoing intracranial pressure (ICP) and brain temperature monitoring. […]
Stroke Reports
Saturday, January 26th, 2013
ATVBAHA: January 17, 2013 Objective—To simultaneously evaluate 14 biomarkers from distinct biological pathways for risk prediction of ischemic stroke, including biomarkers of hemostasis, inflammation, and endothelial activation as well as chemokines and adipocytokines. Methods and Results—The Prospective Epidemiological Study on Myocardial Infarction (PRIME) is a cohort of 9771 healthy men 50 to 59 years of […]
Stroke Reports
Saturday, January 26th, 2013
STROKEAHA: January 3, 2013 Background and Purpose—Wake-up ischemic stroke (WUIS) patients are not eligible for thrombolysis; the a priori hypothesis was that thrombolysis of selected WUIS patients who meet clinical and imaging criteria for treatment is associated with better outcomes. Methods—The sample consisted of consecutive WUIS patients who fulfilled predefined criteria: (1) were last seen normal […]
Stroke Reports
Saturday, January 26th, 2013
STROKEAHA: January 3, 2013 Systematic Review and Meta-Analysis of Observational Studies and Randomized Trials Background and Purpose—Although experimental data suggest that statin therapy may improve neurological outcome after acute cerebral ischemia, the results from clinical studies are conflicting. We performed a systematic review and meta-analysis investigating the relationship between statin therapy and outcome after ischemic stroke. […]
Stroke Reports
Saturday, January 26th, 2013
STROKEAHA: December 27, 2012 Myth or Reality? Cannabis, which is the most widely used recreational substance in the world, is considered by many consumers as safe with few negative side effects.1 This opinion is somehow strengthened by the fact that cannabis was also shown to have therapeutic applications.2 Cannabis is obtained from the plant Cannabis sativa and its varieties Cannabis indica and Cannabis […]
Stroke Reports
Thursday, January 17th, 2013
STROKEAHA: January 15, 2013 The field of stroke genetics continues to make substantive advances. Large-scale partnerships have led to meta-analyses in ischemic and hemorrhagic stroke, which are yielding reproducible genetic risk factors. Most ischemic stroke risk factors seem to be specific to type, for example, large-vessel stroke. Progress is being made in understanding the pathophysiology of […]
Stroke Reports
Thursday, January 17th, 2013
Stroke.ahajournals.org: 1/10/13 Background and Purpose—Current literature provides mixed evidence on disparities by race/ethnicity and socioeconomic status in discharge outcomes after hospitalization for acute ischemic stroke. Using comprehensive data from 8 states, we sought to compare inpatient mortality and length of stay by race/ethnicity and socioeconomic status. Methods—We examined all 2007 hospitalizations for acute ischemic stroke in […]
Stroke Reports
Thursday, January 17th, 2013
STROKEAHA: January 10, 2013 Background and Purpose—Strokes have especially devastating implications if they occur early in life; however, only limited information exists on the characteristics of acute cerebrovascular disease in young adults. Although risk factors and manifestation of atherosclerosis are commonly associated with stroke in the elderly, recent data suggests different causes for stroke in the […]
Stroke Reports
Thursday, January 17th, 2013
STROKEAHA: January 10, 2013 Background and Purpose—Selective serotonin reuptake inhibitors (SSRIs) are widely prescribed after stroke. We aimed to investigate whether potential antiplatelet or vasospastic effects have important clinical implications. Methods—Using data from Danish medical registries, we did a nationwide follow-up study among ischemic stroke patients between 2003 and 2009. We identified 5833 SSRI users, and […]
Stroke Reports
Thursday, January 17th, 2013
JACC: 11/20/12 The medical profession should play a central role in evaluating the evidence related to drugs, devices, and procedures for the detection, management, and prevention of disease. When properly applied, expert analysis of available data on the benefits and risks of these therapies and procedures can improve the quality of care, optimize patient outcomes, and favorably […]
